| 英文名稱 | Anti-ANGPTL5/FITC |
| 中文名稱 | FITC標記的血管生成素相關蛋白5 |
| 別 名 | Angiopoietin like 5; Angiopoietin related protein 5; Angiopoietin-like protein 5; Angiopoietin-related protein 5; ANGL5_HUMAN; ANGPTL 5; ANGPTL5; Fibrinogen like; hide |
| 說 明 書 | 100ul |
| 研究領域 | 心血管 生長因子和激素 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Human, Chicken, Pig, Horse, Sheep, |
| 產品應用 | IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 41kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ANGPTL5 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產品介紹 | background:
Angptl5 (angiopoietin-like 5) is a 388 amino acid secreted protein that contains one fibrinogen C-terminal domain and is primarily expressed in adult heart tissue. The gene encoding Angptl5 maps to human chromosome 11. With approximay 135 million base pairs and 1,400 genes, chromosome 11 comprises approximay 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-angiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.
Subcellular Location:
Secreted (Potential).
Tissue Specificity:
Mainly expressed in adult heart.
Similarity:
Contains 1 fibrinogen C-terminal domain.
Database links:Entrez Gene: 253935 Human Omim: 607666 Human SwissProt: Q86XS5 Human Unigene: 318370 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
