MOR- urine test diagnostic reagent
English abbreviations: MOR, MOP
Detect contraband: Morphine, heroin, opium, codeine, federal, cough, water (shake, head, water), yellow, skin (material), and, other, opioid, drugs, test: urine
Clinical application: drug control system, drug rehabilitation center, a screening, immigration and quarantine, family rehabilitation and so on.
Detection threshold: 300ng/ml.
Detection method of MOR- urine test diagnostic reagent: colloidal gold method.
Product characteristics: used to qualitatively detect the presence of MOR morphine in urine.
[product name]
General name: Requirements for Morphine Diagnostic Kit (colloidal gold)
English Name: Morphine, Diagnostic, Kit (Colloidal, Gold)
[packing specifications] urine cup type; 40T / box
[intended use] this product is used to qualitatively detect morphine in human urine.
MOR- diagnostic reagent. [urine test principle]
Morphine (Morphine) is a Opioid alkaloid extracted from Opioid. It is a pure Opioid receptor agonist and has powerful analgesic effect. Therefore, morphine is an analgesic drug in medicine. This kind of substance has the euphoria at first, can not concentrate, can produce the illusion phenomenon, the excessive use causes the acute poisoning, extremely easy to bear the tolerance and the addiction. Morphine mainly excreted in urine by the kidneys, and morphine accounted for 2-12%, most of which (60-80%) were morphine gluconate. Class Opioid poisons (including Opioid, morphine, codeine) enter the body and are metabolized primarily by the liver and are rapidly de acylated into 6-, which is further reduced to morphine. Therefore, the presence of morphine or its metabolites in urine and exceeding the threshold indicates that Opioid prohibited substances have been used.
The antibody - antigen - specific binding reaction and immune membrane chromatography technique were used to detect morphine in human urine by immune competitive inhibition method. That is, protein labeled morphine (morphine carrier), which competes with morphine in urine, competes for antigen binding sites on limited antibodies.
A detection cup cover strip, the strip test area (T) coated -BSA morphine carrier conjugates, the other end is fixed with morphine monoclonal antibody colloidal gold disk. If the urine containing morphine, morphine in urine and immobilized on nitrocellulose membrane labeled colloidal gold in morphine competition on morphine antibody antigen binding sites, when the above threshold concentration of morphine concentration in urine to product design, they will be the first with morphine monoclonal antibody and colloidal gold paper occupy all the binding sites of morphine antigen antibody, thus preventing the colloidal gold detection zone on morphine antibody and on the membrane of morphine combined detection area can not capture the colloidal gold particles without red ribbon showed positive results. If no concentration of morphine or morphine in urine concentration is below the threshold, the antibody colloidal gold of morphine combined with morphine or not is not saturated, so the colloidal gold on morphine combined with antibody and the detection regions on the membrane of morphine, the detection zone to capture the colloidal gold particles appear red ribbon, negative results.
In the strip quality control area (C) coated with Goat anti mouse IgG polyclonal antibody kit, to indicate the reaction system is working properly. The appearance of quality control lines is not related to the presence of prohibited substances or prohibited substances. The appearance of the quality control zone (C) ribbons showed that: 1. The amount of samples added was sufficient.
[main ingredients]
1. morphine test cup cover (containing a package of anti morphine monoclonal antibodies, Sheep anti rat IgG and morphine -BSA test strip), each person aluminum foil bag packaging.
2. instructions 1 copies.
3. the timer is not supplied in the package, please bring it yourself.
[storage conditions and period] stored at 4-30 C for 24 months. Freeze storage.
. The sample [requirements]
Urine is collected from disposable clean urine cups, and fresh urine is recommended without any special treatment. The urine can be stored at 2-8 DEG C for 2 days, frozen for -20 months, and stored for 1-2 months. Refrigerated samples need to be restored to room temperature before testing. The frozen samples should be compley dissolved and fully mixed before they can be detected. Otherwise, the test results may be affected. Samples collected are to be tested in time.
1. please read the instruction manual carefully before testing.
2. will detect the lid, urine samples and quality control in recovery to room temperature (25 DEG C), in not ready before please don't rip kit kit packaging, storage in advance to the room temperature and then open the package, in order to avoid moisture absorption reagent.
3. remove the kit from the sealed bag and mark the patient or quality control number on the kit.
4. let the patient collect urine directly in the urine cup, and the urine sample should be higher than the minimum line.
5., the professional responsible for the collection of urine sample urine cup, and cover the cup lid. If the lid is not properly pressed, it may cause leakage of the sample in the kit.
6. make the cup cover two angles support the table top, will detect urine cup side pour 15 seconds later, will detect urine cup stand upright.
In 7.3-8 minutes, observe the results on the display window of the cup cover.
8., in order to ensure the accuracy of the inspection, in the process of testing, we can check the quality control products (new testing personnel, new batch products and start testing every day are detected by quality control products). Quality control products are not provided in the kit, and can be made to the manufacturer.
[range of reference]
The minimum detectable amount of this product on morphine was 300ng/ml, more than 300ng/ml positive, 300ng/ml negative ".
[judgment and interpretation of the results]
Negative: two ribbons appear, that is, the line of inspection (T line) and the quality control line (C line), each of which appears a red line. No morphine prohibited substances are present in the sample

Positive: only a red line appeared on the quality control line (C line). No lines appeared on the test line (T line), indicating the presence of morphine prohibited substances in the sample.
Invalid: the quality control line (C line) does not appear. In any case, the C lines shall be formed to indicate the addition and correct operation. The C line does not appear, indicating that the test result is uncertain and should be redone.
Note: a very thin ribbon appears on the test line (T line), indicating that the concentration of morphine in the urine is close to the detection threshold of the reagent strip and that a more accurate and specific method is used to confirm the positive results
[matters needing attention]
1. test operation should comply with safety operation regulations, correctly wear overalls, gloves and so on.
2. urine specimens and all used articles shall be treated as infectious substances.
3. this reagent is only used for qualitative screening and can not determine the content of morphine in urine.
4. a new collection vessel and pipette can be used in each urine sample to prevent contamination of the urine.
5. test new urine samples if suspected of contamination of urine samples.
[storage] original packaging at 4-30 degrees, avoid light storage, not frozen, in the validity period.
[validity] 24 months

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【公司名稱】 廣州健侖生物科技有限公司

【市場部】       楊永漢
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【公司地址】 廣州市清華科技園健新基地番禺石樓鎮健啟路63號二期2幢101-103室