Anti-Phospho-Bad(Ser155),磷酸化相關死亡促進因子抗體科研產品介紹:
Bad is a member of the Bcl2 family and acts to promote apoptosis by forming heterodimers with the survival proteins Bcl2 and BclxL, thus preventing them from binding with BAX. Bad is found on the outer mitochondrial membrane and, once phosphorylated in response to growth stimuli, translocates to the cytoplasm. The phosphorylation status of Bad represents a key checkpoint for death or cell survival. JNK-induced phosphorylation of BAD serine 128 promotes the apoptotic role of Bad by opposing the inhibitory effect of growth factor on Bad-mediated apoptosis. Cdc2-induced phosphorylation of Bad serine 128 has an inhibitory effect on its interaction with 14-3-3 proteins. The latter interaction is critical for Bad phosphorylation at serine 155, a site within the BH3 domain that leads to the release of BclxL and the promotion of cell survival. Alternative splicing of this gene results in two transcript variants which encode the same isoform

與“Anti-Phospho-Bad(Ser155),磷酸化相關死亡促進因子抗體科研"有關的產品:
Anti-CD337/NKp30/NCR3(Natural killer cell p30-related protein) 細胞毒性受體NK-p30抗體
Anti-CD328/Siglec-7(Sialic acid-binding Ig-like lectin 7) 唾液酸結合性免疫球蛋白樣凝集素7抗體
Anti-KLRF1/NKp80 細胞毒性受體NK-p80抗體
Anti-Cdc6 細胞分裂周期蛋白6抗體
Anti-CD339/Jagged1 抗Jagged1/CD339抗體
Anti-Cdc34(Cell Division Cycle protein 34) 細胞周期調控因子34
Anti-CDK1 (Cyclin-Dependent Kinase 1) 周期素依賴性激酶1抗體
Anti-CDK2 (Cyclin-Dependent Kinase 2) 周期素依賴性激酶2抗體
Anti-CDK3 (cyclin-dependent kinase 3) 周期素依賴性激酶3抗體
Anti-CDK4 (cyclin-dependent kinase 4) 周期素依賴性激酶4抗體
Anti-Phospho-Bad(Ser155),磷酸化相關死亡促進因子抗體科研產品詳情:
產品編號:HRK-3057R
產品規格: 0.1ml/0.2ml
產品別名:Bad (phospho S155); Bad (phospho Ser155); p-Bad (S155);p- Bad (Ser155); p-Bad (phospho Ser155); BBC 2; BBC2; BBC6; Bcl 2 Antagonist of Cell Death; Bcl 2 Binding Component 6; BCL X / BCL 2 Binding Protein; BCL X Binding Protein; Bcl XL/Bcl 2 Associated Death Promoter; Bcl-2-like protein 8; Bcl2 antagonist of cell death; BCL2 antagonist of cell death protein; BCL2 associated agonist of cell death; Bcl2 Associated Death Promoter; BCL2 binding component 6; BCL2 binding protein; Bcl2 Like 8 Protein; Bcl2-L-8; BCL2L8; BclXL; Proapoptotic BH3 Only Protein; BAD_HUMAN; Bcl-2-binding component 6
產品價格:詢價(電詢或客服)
產品用途:科研實驗
貯 存: 貯存于-20℃.
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